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> :: LPCINC

SHINE MOUSE PLATFORM

To increase the success rate for antibody therapies, the forerunners of the biopharmaceutical market today, it is imperative to discover many competitive antibody candidates early in the development stage. For this reason, antibody production technology is gaining attention. In particular, the use of human antibody mouse platform technology which is optimized in vivo is steadily growing.



Fully human antibody production technology has evolved from; Phage display platform → to 1st generation human antibody mouse platform → to 2nd generation human antibody mouse platform. Since human antibodies (originating) from mouse undergo a natural selection process, they have superior physical properties pertaining to affinity, solubility, and stability and can be quickly and efficiently chosen for use in clinical medicine.



Taking into account the increasing complexity of the targets demanded in today’s industry, GENUV is developing an upgraded SHINE MOUSE® with increased antibody variety in comparison with the existing 2nd generation human antibody mouse platforms.